abstract：:Potential iatrogenic mood and cognitive declines associated with long-acting opioid therapy were examined in 19 patients receiving long-acting oral opioid medications and compared to ten patients receiving usual care. Pain, mood, and cognitive function were measured before and after achieving stable doses. In addition...

journal_title：Journal of pain and symptom management

authors： Haythornthwaite JA,Menefee LA,Quatrano-Piacentini AL,Pappagallo M

更新日期：1998-03-01 00:00:00

abstract：:This study describes an observational system (modified infant pain scale, MIPS) with elements from a previously published observational scale and from assessments of video-recorded infant facial expressions. It was designed to allow rapid and repeated assessments of pain in infants after brief training by an observer ...

journal_title：Journal of pain and symptom management

authors： Buchholz M,Karl HW,Pomietto M,Lynn A

更新日期：1998-02-01 00:00:00

abstract：:The intravenous (i.v.) administration of opioids to neonates is a common method of providing analgesia in the intensive care setting. This paper reviews and critiques the studies that have investigated this intervention. The studies are grouped into four major areas: pharmacokinetic studies; i.v. opioids for anesthesi...

journal_title：Journal of pain and symptom management

authors： Franck LS,Miaskowski C

更新日期：1998-01-01 00:00:00

abstract：:This report describes an 18-month project to make acute and cancer pain management an institutional priority in Southeastern Wisconsin health-care facilities. Facility-based teams, each of which included a nurse in a leadership position, were recruited to participate in a project based on the Cancer Pain Role Model Pr...

journal_title：Journal of pain and symptom management

authors： Weissman DE,Griffie J,Gordon DB,Dahl JL

更新日期：1997-11-01 00:00:00

abstract：:Many painful disorders, including joint dysfunctions such as rheumatoid arthritis (RA) or temporomandibular joint disorders (TMD), are associated with hyperthermia of the overlying skin. The same is true of certain intractable chronic pain conditions, such as chronic orofacial pain, which may be associated with TMD. W...

journal_title：Journal of pain and symptom management

authors： Anbar M,Gratt BM

更新日期：1997-10-01 00:00:00

abstract：:Part I of this two-part paper employs a comparative design to compare primary family caregivers' assessments of lung cancer patients' symptom distress with patients' own perceptions of symptom distress in the home setting. Part II describes the results of the qualitative component of this research. A convenience sampl...

journal_title：Journal of pain and symptom management

authors： Lobchuk MM,Kristjanson L,Degner L,Blood P,Sloan JA

更新日期：1997-09-01 00:00:00

abstract：:The identification of a neuropathic pain syndrome in a cancer patient requires a focused clinical evaluation based on knowledge of common neuropathic pain syndromes. If a tumor is directly involved in the etiology of the pain, oncologic treatment is an initial consideration and may include surgery, radiation, or chemo...

journal_title：Journal of pain and symptom management

authors： Martin LA,Hagen NA

更新日期：1997-08-01 00:00:00

abstract：:Data on pain prevalence and severity were collected prospectively from advanced cancer patients as an integral part of two service evaluations. Six multidisciplinary palliative care teams working in Ireland formed the basis of one study and five teams based in the South of England were included in the second. A total ...

journal_title：Journal of pain and symptom management

authors： Higginson IJ,Hearn J

更新日期：1997-07-01 00:00:00

abstract：:Cancer patients requiring strong opioid analgesia (n = 202; mean age, 61.5 years; range, 18-89 years; 55% men) were recruited from 38 United Kingdom palliative care centers into a randomized, open, two-period, crossover study comparing transdermal fentanyl with sustained-release oral morphine. Patients received one tr...

journal_title：Journal of pain and symptom management

authors： Ahmedzai S,Brooks D

更新日期：1997-05-01 00:00:00

abstract：:The purpose of this randomized controlled community trial is to evaluate the effects of a community intervention utilizing opinion leaders and educational strategies on the cancer pain management knowledge, attitudes, and the practices of physicians and nurses, and cancer pain reported by patients. Six Minnesota commu...

journal_title：Journal of pain and symptom management

authors： Elliott TE,Murray DM,Oken MM,Johnson KM,Braun BL,Elliott BA,Post-White J

更新日期：1997-04-01 00:00:00

abstract：:The safety and efficacy of intraspinal opioids as therapy for selected patients with cancer pain are well-established. The choice of the appropriate drug is influenced by many variables that are to date incompletely elucidated. The cost of therapy is an increasingly important component of decision-making. This report ...

journal_title：Journal of pain and symptom management

authors： Manfredi PL,Chandler SW,Patt R,Payne R

更新日期：1997-02-01 00:00:00

abstract：:Indwelling subcutaneous cannula for the administration of intermittent morphine boluses postoperatively have been used in several centers as an alternative to intramuscular (IM) injections. We introduced this technique to our hospital, assessed it for complications in 220 children, and conducted a survey to see if nur...

journal_title：Journal of pain and symptom management

authors： Lamacraft G,Cooper MG,Cavalletto BP

更新日期：1997-01-01 00:00:00

abstract：:Pruritus is a common opioid side effect and can be so severe that opioid therapy must be modified or abandoned. Antihistamines, opioid antagonists, and propofol have been proposed as treatment options, but none is universally effective. The use of intranasal butorphanol, an opioid agonist-antagonist, for pruritus has ...

journal_title：Journal of pain and symptom management

authors： Dunteman E,Karanikolas M,Filos KS

更新日期：1996-10-01 00:00:00

abstract：:Cancer patients suffer multiple symptoms and require numerous drug therapies. Parenteral administration of multiple medications from a single container can simplify drug regimens for patient self-administration. This simplification reduces drug preparation costs and risk of infection. Therapeutic options are limited b...

journal_title：Journal of pain and symptom management

authors： Chandler SW,Trissel LA,Weinstein SM

更新日期：1996-09-01 00:00:00

abstract：:A self-administered pain assessment tool called the Pain-O-Meter (POM) was developed for the purposes of improving assessment and management of pain in acute and chronic pain patients. The POM is a hard, white, plastic tool that measures 8-in. long by 2-in. wide and 1-in. thick. Two methods for assessing pain are loca...

journal_title：Journal of pain and symptom management

authors： Gaston-Johansson F

更新日期：1996-09-01 00:00:00

abstract：:The aims of this study were (a) to estimate the prevalence of pain and eight other common symptoms in a large population of patients with advanced cancer from different palliative care centers, and (b) to assess the differences in prevalence of the symptoms by primary site. In 1990-1991, the prevalence of eight major ...

journal_title：Journal of pain and symptom management

authors： Vainio A,Auvinen A

更新日期：1996-07-01 00:00:00

abstract：:Loperamide was used to provide a source of opioid-induced constipation in healthy volunteers. Each volunteer took a sequence of three dose levels of loperamide. One of three laxatives was used to counterbalance the effect of loperamide and restore bowel function to what the individual considered normal at each stage b...

journal_title：Journal of pain and symptom management

authors： Sykes NP

更新日期：1996-06-01 00:00:00

abstract：:Five patients with chronic nonmalignant pain were transferred from other analgesics to oral methadone. The method of transferring to oral methadone is described and issues of cost effectiveness, convenience, improved analgesia, and adverse effects are discussed. Oral methadone may provide a cost-effective alternative ...

journal_title：Journal of pain and symptom management

authors： Gardner-Nix JS

更新日期：1996-05-01 00:00:00

abstract：:Effective strategies to increase the visibility of pain and the accountability of health-care professionals for the treatment of pain are needed to improve the quality of pain management. Critical pathways are tools used to plan and document care for patients within a system of case management. Case management models ...

journal_title：Journal of pain and symptom management

authors： Gordon DB

更新日期：1996-04-01 00:00:00

abstract：:Initial dose finding in patients with cancer pain who are started on TTS fentanyl (Duragesic, TTS-F) is often unsatisfactory with currently recommended doses and intervals. Acknowledging that studies reveal a "psuedo steady state" 15 to 20 hr after application of TTS-F, we prospectively investigated an increased initi...

journal_title：Journal of pain and symptom management

authors： Korte W,de Stoutz N,Morant R

更新日期：1996-03-01 00:00:00

abstract：:The relationships between plasma morphine and metabolite (M3G and M6G) concentrations and analgesic efficacy were investigated in an open study of 39 cancer pain patients receiving chronic oral morphine therapy with either morphine sulfate solution or controlled-release morphine tablets. There were no differences in m...

journal_title：Journal of pain and symptom management

authors： Faura CC,Moore RA,Horga JF,Hand CW,McQuay HJ

更新日期：1996-02-01 00:00:00

abstract：:Radiotherapy remains the primary treatment of malignant epidural spinal cord compression. Therapeutic success depends on diagnosis before the development of neurological compromise and the prompt initiation of radiotherapy. Radiotherapy alone is effective in over 85% of cases of spinal cord compression that occur in h...

journal_title：Journal of pain and symptom management

authors： Janjan NA

更新日期：1996-01-01 00:00:00

abstract：:The purpose of this retrospective study was to determine the prevalence of alcoholism among terminally ill cancer patients when assessed by multidisciplinary interviews and by the CAGE Questionnaire. We reviewed the charts of 100 consecutive patients assessed by a multidisciplinary team for the presence of alcoholism ...

journal_title：Journal of pain and symptom management

authors： Bruera E,Moyano J,Seifert L,Fainsinger RL,Hanson J,Suarez-Almazor M

更新日期：1995-11-01 00:00:00

abstract：:A 39-year-old woman with breast cancer metastatic to bone presented with acute hip pain marginally responsive to escalating doses of opioid analgesics. Pathologic pelvic fractures were present and there were minimal clinical indicators of infection, but the severity and intractable nature of the pain prompted further ...

journal_title：Journal of pain and symptom management

authors： Mackey JR,Birchall I,MacDonald N

更新日期：1995-10-01 00:00:00

abstract：:Oral amitriptyline has been used as an analgesic in a wide range of pain settings. Despite long-term availability of a parenteral form, the few reports about this formulation have been limited to pharmacokinetic studies in normal volunteers, trials in depressed patients, and analyses of electroencephalogram (EEG) acti...

journal_title：Journal of pain and symptom management

authors： Collins JJ,Kerner J,Sentivany S,Berde CB

更新日期：1995-08-01 00:00:00

abstract：:Accumulation of active (toxic) metabolites of opioids might explain cases of opioid toxicity when high doses are used for long periods of time. Other mechanisms of late toxicity of opioids may be found at the receptor level. Whatever the cause, a change of opioids using equianalgesic doses can be expected to improve s...

journal_title：Journal of pain and symptom management

authors： de Stoutz ND,Bruera E,Suarez-Almazor M

更新日期：1995-07-01 00:00:00

abstract：:Celiac plexus blockade with ethanol is a widely accepted modality of pain control for adults with cancer pain. The role of interventional strategies in children is less well established. A 7-year-old child with abdominal pain secondary to a Wilms tumor was treated with neurolytic celiac plexus blockade. This resulted ...

journal_title：Journal of pain and symptom management

authors： Staats PS,Kost-Byerly S

更新日期：1995-05-01 00:00:00

abstract：:Diarrhea is a distressing symptom that limits the quality of life in terminally ill patients. In these patients, many factors can affect intestinal secretion, absorption, and motility, including drugs, infective agents, antibiotics, chemotherapy, radiotherapy, surgery, malnutrition, neuroendocrine tumors, and mechanic...

journal_title：Journal of pain and symptom management

authors： Mercadante S

更新日期：1995-05-01 00:00:00

abstract：:The effects of dronabinol on appetite and weight were evaluated in 139 patients with AIDS-related anorexia and > or = 2.3 kg weight loss in a multi-institutional study. Patients were randomized to receive 2.5 mg dronabinol twice daily or placebo. Patients rated appetite, mood, and nausea by using a 100-mm visual analo...

journal_title：Journal of pain and symptom management

authors： Beal JE,Olson R,Laubenstein L,Morales JO,Bellman P,Yangco B,Lefkowitz L,Plasse TF,Shepard KV

更新日期：1995-02-01 00:00:00

abstract：:Research in affective disorders has shown that there is a clear link between mood and light exposure, and that exposure to bright wide-spectrum light (phototherapy) may be an effective antidepressant treatment in some clinical situations. Cancer patients, especially those in the terminal phase of illness, have a high ...

journal_title：Journal of pain and symptom management

authors： Cohen SR,Steiner W,Mount BM

更新日期：1994-11-01 00:00:00

abstract：:In a prospective study, the prevalence of 15 physical symptoms and symptom groups was evaluated in 1635 cancer patients referred to a pain clinic. In addition to pain, patients suffered an average of 3.3 symptoms: insomnia (59%), anorexia (48%), constipation (33%), sweating (28%), nausea (27%), dyspnea (24%), dysphagi...

journal_title：Journal of pain and symptom management

authors： Grond S,Zech D,Diefenbach C,Bischoff A

更新日期：1994-08-01 00:00:00

abstract：:The need to treat dehydration in terminally ill patients to minimize symptom distress remains a controversial issue. Hypodermoclysis (HDC) is a simple technique for rehydration that offers many advantages over the intravenous route. In this prospective open study of 100 consecutive patients who died on a palliative ca...

journal_title：Journal of pain and symptom management

authors： Fainsinger RL,MacEachern T,Miller MJ,Bruera E,Spachynski K,Kuehn N,Hanson J

更新日期：1994-07-01 00:00:00

abstract：:US health-care policy and recent literature are reviewed to examine whether there are reimbursement barriers to acute and cancer pain management. The available evidence suggests that lack of coverage and uneven reimbursement policies for health care including prescription drugs, medical equipment, and professional ser...

journal_title：Journal of pain and symptom management

authors： Joranson DE

更新日期：1994-05-01 00:00:00

abstract：:After years of second-class status, supportive care is increasingly being recognized for its importance. Included in this recognition is a concern for making more explicit the long-held conviction within medicine that no goal can logically be more important than optimal patient functioning and well-being. This effort ...

journal_title：Journal of pain and symptom management

authors： Cella DF

更新日期：1994-04-01 00:00:00

abstract：:Pain was measured and analgesic treatment examined in 131 children and adolescents, 8-17 years of age, for 5 days after surgery. Analgesic data were converted to 10 mg intramuscular morphine-equivalent doses (IMMSEQ) and were designated appropriate or inappropriate for body weight. Analgesic onset, peak, and duration ...

journal_title：Journal of pain and symptom management

authors： Tesler MD,Wilkie DJ,Holzemer WL,Savedra MC

更新日期：1994-02-01 00:00:00

abstract：:The doses of opioid analgesics required to control pain in patients with cancer may result in somnolence and reduced interaction with family members. Psychostimulants such as dextroamphetamine (DA, Dexedrine) or methylphenidate (MP, Ritalin) have been used in adults to counteract the sedation of opioid analgesia. We r...

journal_title：Journal of pain and symptom management

authors： Yee JD,Berde CB

更新日期：1994-02-01 00:00:00

abstract：:The use of intrathecal diamorphine via an implanted portal system is described for pain control in a patient suffering from vertebral metastatic disease. The complication of myoclonic spasms affecting the lower half of the body occurred after 14 days, when increasing the bolus dose to 40 mg. The spasms lasted for 3 hr...

journal_title：Journal of pain and symptom management

authors： Cartwright PD,Hesse C,Jackson AO

更新日期：1993-10-01 00:00:00

abstract：:To define changes in sleep and subjective fatigue associated with localized radiation treatment, and to determine their relationship to interleukin-1B (IL-1), we prospectively followed 15 men, none of whom were depressed during 8 wk of radiation treatment for localized prostate cancer. Each patient rated fatigue daily...

journal_title：Journal of pain and symptom management

authors： Greenberg DB,Gray JL,Mannix CM,Eisenthal S,Carey M

更新日期：1993-05-01 00:00:00

abstract：:To delineate dose ranges, utilization patterns, and the frequency and types of problems encountered, we retrospectively reviewed the medical records of 46 patients with sickle hemoglobinopathies who used patient-controlled analgesia (PCA) a total of 92 times for the management of vasooclusive pain. Patients varied wid...

journal_title：Journal of pain and symptom management

authors： Shapiro BS,Cohen DE,Howe CJ

更新日期：1993-01-01 00:00:00

abstract：:Inadequate nursing education is a major impediment to effective pain relief for cancer patients throughout the world. This study was conducted to identify the level of cancer pain knowledge among baccalaureate student nurses and to determine whether specific activities affect this level of knowledge. Two questionnaire...

journal_title：Journal of pain and symptom management

authors： Sheehan DK,Webb A,Bower D,Einsporn R

更新日期：1992-11-01 00:00:00